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Clinical investigation: head and neck
Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer K.Kian Ang, Andy Trotti, Barry W Brown, Adam S Garden, Robert L Foote, William H Morrison, Fady B Geara, Douglas W Klotch, Helmuth Goepfert, Lester J Peters pages 571-578 Abstract | Full Text | Full-Text PDF (180 KB)
Potential role of intensity-modulated radiotherapy in the treatment of tumors of the maxillary sinus Elizabeth J Adams, Christopher M Nutting, David J Convery, Vivian P Cosgrove, J.Michael Henk, David P Dearnaley, Steve Webb pages 579-588 Abstract | Full Text | Full-Text PDF (544 KB)
Important prognostic factors in patients with skull base erosion from nasopharyngeal carcinoma after radiotherapy Tai-Xiang Lu, Wei-Yuan Mai, Bin S Teh, Yong-Hong Hu, Hsin H Lu, J.Kam Chiu, L.Steven Carpenter, Shiao Y Woo, E.Brian Butler pages 589-598 Abstract | Full Text | Full-Text PDF (120 KB)
Hypothyroidism incidence after multimodality treatment for stage III and IV squamous cell carcinomas of the head and neck A.Dimitrios Colevas, Richard Read, John Thornhill, Sudeshna Adak, Roy Tishler, Paul Busse, Yi Li, Marshall Posner pages 599-604 Abstract | Full Text | Full-Text PDF (60 KB)
Clinical investigation: prostate
Phase I/II trial evaluating combined radiotherapy and in situ gene therapy with or without hormonal therapy in the treatment of prostate cancer—A preliminary report Bin S. Teh, Estuardo Aguilar-Cordova, Kenneth Kernen, Chieng-Chung Chou, Moshe Shalev, Maria T. Vlachaki, Brian Miles, Dov Kadmon, Wei-Yuan Mai, James Caillouet, Maria Davis, Gustavo Ayala, Thomas Wheeler, Jett Brady, L.Steve Carpenter, Hsin H. Lu, J.Kam Chiu, Shiao Y. Woo, Timothy Thompson, E.Brian Butler pages 605-613 Abstract | Full Text | Full-Text PDF (80 KB)
A prospective quality-of-life study in men with clinically localized prostate carcinoma treated with radical prostatectomy, external beam radiotherapy, or interstitial brachytherapy W.Robert Lee, M.Craig Hall, Richard P McQuellon, L.Douglas Case, David L McCullough pages 614-623 Abstract | Full Text | Full-Text PDF (96 KB)
Salvage external beam radiotherapy for clinical failure after cryosurgery for prostate cancer Michael J McDonough, John J Feldmeier, Ishmael Parsai, Ralph R Dobelbower, Steven H Selman pages 624-627 Abstract | Full Text | Full-Text PDF (40 KB)
The effect of oral sucralfate on the acute proctitis associated with prostate radiotherapy: a double-blind, randomized trial Andrew Kneebone, Hedy Mameghan, Terry Bolin, Martin Berry, Sandra Turner, John Kearsley, Peter Graham, Richard Fisher, Geoff Delaney pages 628-635 Abstract | Full Text | Full-Text PDF (244 KB)
Argon plasma coagulation for rectal bleeding after prostate brachytherapy Stephen Smith, Kent Wallner, Jason A Dominitz, Ben Han, Lawrence True, Steven Sutlief, Kevin Billingsley pages 636-642 Abstract | Full Text | Full-Text PDF (766 KB)
Clinical investigation: testis
Radiotherapy for stage II testicular seminoma Gunar K Zagars, Alan Pollack pages 643-649 Abstract | Full Text | Full-Text PDF (95 KB)
Clinical investigation: lung
Radiation-induced pulmonary toxicity: a dose-volume histogram analysis in 201 patients with lung cancer Maria L. Hernando, Lawrence B. Marks, Gunilla C. Bentel, Su-Min Zhou, Donna Hollis, Shiva K. Das, Ming Fan, Michael T. Munley, Timothy D. Shafman, Mitchell S. Anscher, Pehr A. Lind pages 650-659 Abstract | Full Text | Full-Text PDF (119 KB)
Induction chemotherapy plus three-dimensional conformal radiation therapy in the definitive treatment of locally advanced non-small-cell lung cancer Sang Sim, Kenneth E Rosenzweig, Rachel Schindelheim, Kenneth K Ng, Steven A Leibel pages 660-665 Abstract | Full Text | Full-Text PDF (70 KB)
Computed tomography-guided frameless stereotactic radiotherapy for stage I non-small cell lung cancer: a 5-year experience Minoru Uematsu, Akira Shioda, Atsushi Suda, Toshiharu Fukui, Yuichi Ozeki, Yukihiro Hama, James R Wong, Shoichi Kusano pages 666-670 Abstract | Full Text | Full-Text PDF (182 KB)
Clinical investigation: breast
Relationship of sentinel and axillary level I–II lymph nodes to tangential fields used in breast irradiation Pamela J Schlembach, Thomas A Buchholz, Merrick I Ross, Steven M Kirsner, G.Jessica Salas, Eric A Strom, Marsha D McNeese, George H Perkins, Kelly K Hunt pages 671-678 Abstract | Full Text | Full-Text PDF (169 KB)
Second cancers after conservative surgery and radiation for stages I–II breast cancer: identifying a subset of women at increased risk Barbara Fowble, Alexandra Hanlon, Gary Freedman, Nicos Nicolaou, Penny Anderson pages 679-690 Abstract | Full Text | Full-Text PDF (89 KB)
Fatigue, serum cytokine levels, and blood cell counts during radiotherapy of patients with breast cancer Hans Geinitz, Frank B Zimmermann, Peter Stoll, Reinhard Thamm, Walter Kaffenberger, Kai Ansorg, Monika Keller, Raymonde Busch, Dirk van Beuningen, Michael Molls pages 691-698 Abstract | Full Text | Full-Text PDF (89 KB)
Clinical investigation: cervix
Tumor size and oxygenation are independent predictors of nodal diseases in patients with cervix cancer Graham Pitson, Anthony Fyles, Michael Milosevic, James Wylie, Melania Pintilie, Richard Hill pages 699-703 Abstract | Full Text | Full-Text PDF (57 KB)
Clinical investigation: brain
Results of a policy of surveillance alone after surgical management of pediatric low grade gliomas Barbara J Fisher, Christopher C Leighton, Olga Vujovic, David R Macdonald, Larry Stitt pages 704-710 Abstract | Full Text | Full-Text PDF (81 KB)
Neurocognitive outcome in brain metastases patients treated with accelerated-fractionation vs. accelerated-hyperfractionated radiotherapy: an analysis from Radiation Therapy Oncology Group Study 91-04 W.F Regine, C Scott, K Murray, W Curran pages 711-717 Abstract | Full Text | Full-Text PDF (161 KB)
Clinical investigation: pediatric
Results from the IRS-IV randomized trial of hyperfractionated radiotherapy in children with rhabdomyosarcoma—a report from the IRSG1 Sarah S Donaldson, Jane Meza, John C Breneman, William M Crist, Fran Laurie, Stephen J Qualman, Moody Wharam, For the Children’s Oncology Group Soft Tissue Sarcoma Committee (formerly Intergroup Rhabdomyosarcoma Group) representing the Children’s Oncology Group and the Quality Assurance Review Center pages 718-728 Abstract | Full Text | Full-Text PDF (109 KB)
Intraoperative high-dose-rate brachytherapy for the treatment of pediatric tumors: the Ohio State University experience Subir Nag, Douglas Tippin, Frederick B Ruymann pages 729-735 Abstract | Full Text | Full-Text PDF (110 KB)
Clinical investigation: pancreas
Radiotherapy and continuous infusion 5-fluorouracil in patients with nonresectable pancreatic carcinoma Giovanni Boz, Antonino De Paoli, Roberto Innocente, Carlo Rossi, Giancarlo Tosolini, Paolo Pederzoli, Renato Talamini, Mauro G Trovò pages 736-740 Abstract | Full Text | Full-Text PDF (58 KB)
Clinical investigation; anal canal
Elective groin irradiation is not indicated for patients with adenocarcinoma of the rectum extending to the anal canal Noah Taylor, Christopher Crane, John Skibber, Barry Feig, Lee Ellis, Jean-Nicholas Vauthey, Stanley Hamilton, Karen Cleary, Ronelle Dubrow, Thomas Brown, Robert Wolff, Paulo Hoff, Nicholas Sanfilippo, Nora Janjan pages 741-747 Abstract | Full Text | Full-Text PDF (82 KB)
Clinical investigation: skin
Radiotherapy for epithelial skin cancer Jay Locke, Shervin Karimpour, Gwen Young, Mary Ann Lockett, Carlos A Perez pages 748-755 Abstract | Full Text | Full-Text PDF (132 KB)
Clinical investigation: benign disease
Radiation prophylaxis for heterotopic ossification about the hip joint—a multicenter study Michael Heinrich Seegenschmiedt, Hans-Bruno Makoski, Oliver Micke, the German Cooperative Group on Radiotherapy for Benign Diseases pages 756-765 Abstract | Full Text | Full-Text PDF (374 KB)
Long-term results of irradiation for patients with progressive GRAVES’ ophthalmopathy Sheri D Marquez, Bert L Lum, I.Ross McDougall, Shobha Katkuri, Peter S Levin, Michael MacManus, Sarah S Donaldson pages 766-774 Abstract | Full Text | Full-Text PDF (112 KB)
Biology contribution
Adenovirus-mediated overexpression of dominant negative epidermal growth factor receptor-CD533 as a gene therapeutic approach radiosensitizes human carcinoma and malignant glioma cells Guido Lammering, Peck-Sun Lin, Joseph N. Contessa, Jaime L. Hampton, Kristoffer Valerie, Rupert K. Schmidt-Ullrich pages 775-784 Abstract | Full Text | Full-Text PDF (261 KB)
Enhanced apoptosis and radiosensitization by combined 13-CIS-retinoic acid and interferon-α2a; role of RAR-β gene Samuel Ryu, Joseph P Stein, Chung T Chung, Yong J Lee, Jae Ho Kim pages 785-790 Abstract | Full Text | Full-Text PDF (257 KB)
Five-chlorodeoxycytidine, a tumor-selective enzyme-driven radiosensitizer, effectively controls five advanced human tumors in nude mice1 Sheldon Greer, Marcy Alvarez, Marisol Mas, Chandra Wozniak, David Arnold, Anna Knapinska, Christina Norris, Ronald Burk, Alex Aller, Michael Dauphinée pages 791-806 Abstract | Full Text | Full-Text PDF (449 KB)
Extinction of the weakest James W. Denham, Tomas Kron pages 807-819 Abstract | Full Text | Full-Text PDF (192 KB)
High-dose external beam irradiation inhibits neointima formation in stented pig coronary arteries Stefan Verheye, Patrick K Coussement, Mahomed Y Salame, Payam Fallahi, Jianhua Cui, Nicolas A.F Chronos, Spencer B King, Ian R Crocker, Keith A Robinson pages 820-827 Abstract | Full Text | Full-Text PDF (581 KB)
Evaluation of apoptosis and micronucleation induced by reactor neutron beams with two different cadmium ratios in total and quiescent cell populations within solid tumors Shin-ichiro Masunaga, Koji Ono, Yoshinori Sakurai, Masao Takagaki, Tooru Kobayashi, Yuko Kinashi, Minoru Suzuki pages 828-839 Abstract | Full Text | Full-Text PDF (193 KB)
Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model Stefan Walenta, Stacey Snyder, Zishan A Haroon, Rod D Braun, Khalid Amin, David Brizel, Wolfgang Mueller-Klieser, Britton Chance, Mark W Dewhirst pages 840-848 Abstract | Full Text | Full-Text PDF (767 KB)
Physics contribution
An anatomy-based beam segmentation tool for intensity-modulated radiation therapy and its application to head-and-neck cancer Werner De Gersem, Filip Claus, Carlos De Wagter, Wilfried De Neve pages 849-859 Abstract | Full Text | Full-Text PDF (794 KB)
Erratum
Erratum page 865 Full Text | Full-Text PDF (12 KB)
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