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Editorials
Is it time to change the standard of care from CT to MRI for defining the apex of the prostate to accomplish potency-sparing radiotherapy? Mack Roach pages 1-2 Full Text | Full-Text PDF (47 KB)
The good, the bad, and the ugly Diana Stripp, Eli Glatstein pages 3-4 Full Text | Full-Text PDF (49 KB)
Testing new chemoradiation regimens for head-and-neck cancer Avraham Eisbruch, Daniel P. Normolle pages 5-6 Full Text | Full-Text PDF (50 KB)
Concomitant chemotherapy and radiation therapy certainly improves local control Jay S. Cooper, K. Kian Ang pages 7-9 Full Text | Full-Text PDF (52 KB)
Rapid communication
Novel use of zebrafish as a vertebrate model to screen radiation protectors and sensitizers Mary Frances McAleer, Christian Davidson, William Robert Davidson, Brad Yentzer, Steven A. Farber, Ulrich Rodeck, Adam P. Dicker pages 10-13 Abstract | Full Text | Full-Text PDF (193 KB)
Clinical investigation: Prostate
Assessing the impact of an alternative biochemical failure definition on radiation dose response for high-risk prostate cancer treated with external beam radiotherapy Rex Cheung, Susan L. Tucker, Andrew L. Lee, Lei Dong, Ashish Kamat, Louis Pisters, Deborah A. Kuban pages 14-19 Abstract | Full Text | Full-Text PDF (134 KB)
Clinical investigation
Prostate
Vessel-sparing prostate radiotherapy: Dose limitation to critical erectile vascular structures (internal pudendal artery and corpus cavernosum) defined by MRI Patrick W. McLaughlin, Vrinda Narayana, Amichay Meirowitz, Sara Troyer, Peter L. Roberson, Roger Gonda, Howard Sandler, Lon Marsh, Theodore Lawrence, Marc Kessler pages 20-31 Abstract | Full Text | Full-Text PDF (656 KB)
Impact of supplemental external beam radiotherapy and/or androgen deprivation therapy on biochemical outcome after permanent prostate brachytherapy Gregory S. Merrick, Wayne M. Butler, Kent E. Wallner, Robert W. Galbreath, Jonathan H. Lief, Zachariah Allen, Edward Adamovich pages 32-43 Abstract | Full Text | Full-Text PDF (293 KB)
Randomized trial of high- and low-source strength 125I prostate seed implants Vrinda Narayana, Sara Troyer, Vicki Evans, Raymond J. Winfield, Peter L. Roberson, Patrick W. McLaughlin pages 44-51 Abstract | Full Text | Full-Text PDF (293 KB)
Dosimetry and cancer control after low-dose-rate prostate brachytherapy W. Robert Lee, Allan F. deGuzman, Kevin P. McMullen, David L. McCullough pages 52-59 Abstract | Full Text | Full-Text PDF (319 KB)
Factors associated with the frequency of self-intermittent catheterization after prostate brachytherapy David J. Schwartz, Steven E. Schild, William W. Wong, Sujay A. Vora pages 60-63 Abstract | Full Text | Full-Text PDF (75 KB)
Clinical investigation: Lung
Bronchial stenosis: An underreported complication of high-dose external beam radiotherapy for lung cancer? Keith L. Miller, Timothy D. Shafman, Mitchell S. Anscher, Su-Min Zhou, Robert W. Clough, Jennifer L. Garst, Jeffrey Crawford, Julian Rosenman, Mark A. Socinski, William Blackstock, Gregory S. Sibley, Lawrence B. Marks pages 64-69 Abstract | Full Text | Full-Text PDF (170 KB)
Cisplatin/etoposide chemotherapy combined with twice daily thoracic radiotherapy for limited small-cell lung cancer: A clinical Phase II trial Gui-Yuan Chen, Guo-Liang Jiang, Li-Juan Wang, Hao Qian, Xiao-Long Fu, Huajun Yang, Kai-Liang Wu, Sen Zhao pages 70-75 Abstract | Full Text | Full-Text PDF (112 KB)
Clinical investigation: Esophagus
Clinical results of proton beam therapy for cancer of the esophagus Shinji Sugahara, Koichi Tokuuye, Toshiyuki Okumura, Akira Nakahara, Yukihisa Saida, Kenji Kagei, Kiyoshi Ohara, Masaharu Hata, Hiroshi Igaki, Yasuyuki Akine pages 76-84 Abstract | Full Text | Full-Text PDF (191 KB)
Clinical investigation: Rectum
Low bax protein expression correlates with disease recurrence in preoperatively irradiated rectal carcinoma Oliver Nehls, Thomas Okech, Chih-Jen Hsieh, Mario Sarbia, Franz Borchard, Hans-Helmut Gruenagel, Vera Gaco, Rainer Porschen, Michael Gregor, Bodo Klump pages 85-91 Abstract | Full Text | Full-Text PDF (211 KB)
Clinical investigation: Anus
Epidermoid anal cancer: A review of a population-based series of 308 consecutive patients treated according to prospective protocols Per J. Nilsson, Christer Svensson, Sven Goldman, Olle Ljungqvist, Bengt Glimelius pages 92-102 Abstract | Full Text | Full-Text PDF (211 KB)
Clinical investigation: Head and neck
The role of radiotherapy in the treatment of malignant salivary gland tumors Chris H.J. Terhaard, Herman Lubsen, Coen R.N. Rasch, Peter C. Levendag, Hans H.À.M. Kaanders, Reineke E. Tjho-Heslinga, Piet L.A. van Den Ende, Fred Burlage, Dutch Head and Neck Oncology Cooperative Group (NWHHT) pages 103-111 Abstract | Full Text | Full-Text PDF (350 KB)
Malignant parotid tumors: Presentation, clinical/pathologic prognostic factors, and treatment outcomes Surjeet Pohar, Hiram Gay, Paula Rosenbaum, Darren Klish, Jeffrey Bogart, Robert Sagerman, Jack Hsu, Robert Kellman pages 112-118 Abstract | Full Text | Full-Text PDF (110 KB)
Head and neck
Concurrent chemo-radiotherapy with mitomycin C compared with porfiromycin in squamous cell cancer of the head and neck: Final results of a randomized clinical trial Bruce G. Haffty, Lynn D. Wilson, Yung H. Son, Edward I. Cho, Rose J. Papac, Diana B. Fischer, Sara Rockwell, Alan C. Sartorelli, Douglas A. Ross, Clarence T. Sasaki, James J. Fischer pages 119-128 Abstract | Full Text | Full-Text PDF (208 KB)
FDG-PET/CT imaging for preradiotherapy staging of head-and-neck squamous cell carcinoma David L. Schwartz, Eric Ford, Joseph Rajendran, Bevan Yueh, Marc D. Coltrera, Jeffery Virgin, Yoshimi Anzai, David Haynor, Barbara Lewellyn, David Mattes, Juergen Meyer, Mark Phillips, Michael Leblanc, Paul Kinahan, Kenneth Krohn, Janet Eary, George E. Laramore pages 129-136 Abstract | Full Text | Full-Text PDF (304 KB)
Clinical investigation: Cervix
Relations between non–protein sulfydryl levels in the nucleus and cytoplasm, tumor oxygenation, and clinical outcome of patients with uterine cervical carcinoma David W. Hedley, Trudey Nicklee, Fernando Moreno-Merlo, Melania Pintilie, Anthony Fyles, Michael Milosevic, Richard P. Hill pages 137-144 Abstract | Full Text | Full-Text PDF (225 KB)
Regional hyperthermia combined with radiotherapy for uterine cervical cancers: A multi-institutional prospective randomized trial of the international atomic energy agency Arumugam Vasanthan, Michihide Mitsumori, Jeong Ho Park, Zeng Zhi-Fan, Zhong Yu-Bin, Praskovya Oliynychenko, Hideo Tatsuzaki, Yoshiaki Tanaka, Masahiro Hiraoka pages 145-153 Abstract | Full Text | Full-Text PDF (255 KB)
Long-term results of adjuvant hypofractionated radiotherapy for breast cancer in elderly patients Cécile Ortholan, Jean-Michel Hannoun-Lévi, Jean-Marc Ferrero, Rémy Largillier, Adel Courdi pages 154-162 Abstract | Full Text | Full-Text PDF (155 KB)
Analysis of axillary coverage during tangential radiation therapy to the breast Julia Reznik, M.Giulia Cicchetti, Barbara Degaspe, T.J. Fitzgerald pages 163-168 Abstract | Full Text | Full-Text PDF (309 KB)
Acute complications of MammoSite brachytherapy: A single institution's initial clinical experience Jennifer L. Harper, Joseph M. Jenrette, Kenneth N. Vanek, Eric G. Aguero, William E. Gillanders pages 169-174 Abstract | Full Text | Full-Text PDF (171 KB)
Clinical investigation: Hodgkin's disease
Mid- and post-ABVD gallium scanning predicts for recurrence in early-stage Hodgkin's disease Andrea K. Ng, M.V.Patricia Bernardo, Barbara Silver, Annick Van Den Abbeele, Mary Ann Stevenson, David C. Fisher, Peter M. Mauch pages 175-184 Abstract | Full Text | Full-Text PDF (171 KB)
Clinical investigation: Brain
Temozolomide and concomitant whole brain radiotherapy in patients with brain metastases: A phase II randomized trial Eugènia Verger, Miguel Gil, Ricardo Yaya, Núria Viñolas, Salvador Villà, Teresa Pujol, Llorenç Quintó, Francesc Graus pages 185-191 Abstract | Full Text | Full-Text PDF (113 KB)
Repeat radiosurgery for idiopathic trigeminal neuralgia Bruce E. Pollock, Robert L. Foote, Michael J. Link, Scott L. Stafford, Paul D. Brown, Paula J. Schomberg pages 192-195 Abstract | Full Text | Full-Text PDF (72 KB)
Normal tissues
ATM sequence variants are predictive of adverse radiotherapy response among patients treated for prostate cancer Jamie A. Cesaretti, Richard G. Stock, Steven Lehrer, David A. Atencio, Jonine L. Bernstein, Nelson N. Stone, Sylvan Wallenstein, Sheryl Green, Karen Loeb, Marisa Kollmeier, Michael Smith, Barry S. Rosenstein pages 196-202 Abstract | Full Text | Full-Text PDF (153 KB)
Biology contributions
Monoclonal antibody to HER-2/neu receptor enhances radiosensitivity of esophageal cancer cell lines expressing HER-2/neu oncoprotein Shinsuke Sato, Yoshiaki Kajiyama, Masahiko Sugano, Yoshimi Iwanuma, Hiroshi Sonoue, Toshiharu Matsumoto, Keisuke Sasai, Masahiko Tsurumaru pages 203-211 Abstract | Full Text | Full-Text PDF (392 KB)
Susceptibility of cancer cells to β-lapachone is enhanced by ionizing radiation Heon Joo Park, Ki-Jung Ahn, Seung-Do Ahn, Eunkyung Choi, Sang Wook Lee, Brent Williams, Eun Jung Kim, Robert Griffin, Erik A. Bey, William G. Bornmann, Jinming Gao, Heon Jin Park, David A. Boothman, Chang W. Song pages 212-219 Abstract | Full Text | Full-Text PDF (252 KB)
Impact of tumor repopulation on radiotherapy planning Jian Z. Wang, X. Allen Li pages 220-227 Abstract | Full Text | Full-Text PDF (295 KB)
Physics contributions
Quantification of shape variation of prostate and seminal vesicles during external beam radiotherapy Kirsten E.I. Deurloo, Roel J.H.M. Steenbakkers, Lambert J. Zijp, Josien A. de Bois, Peter J.C.M. Nowak, Coen R.N. Rasch, Marcel van Herk pages 228-238 Abstract | Full Text | Full-Text PDF (376 KB)
Influence of calculation model on dose distribution in stereotactic radiotherapy for pulmonary targets Ulrich Haedinger, Thomas Krieger, Michael Flentje, Joern Wulf pages 239-249 Abstract | Full Text | Full-Text PDF (424 KB)
Randomized trial on two types of thermoplastic masks for patient immobilization during radiation therapy for head-and-neck cancer Lena Sharp, Freddi Lewin, Hemming Johansson, David Payne, Ansi Gerhardsson, Lars Erik Rutqvist pages 250-256 Abstract | Full Text | Full-Text PDF (147 KB)
Minimizing urinary bladder radiation dose during brachytherapy for carcinoma of the cervix using balloon inflation technique Kamal Malaker, Vishnu Shukla, Harold D'Souza, Henry Weatherburn pages 257-266 Abstract | Full Text | Full-Text PDF (510 KB)
A practical approach to thermography in a hyperthermia/magnetic resonance hybrid system: Validation in a heterogeneous phantom Johanna Gellermann, Waldemar Wlodarczyk, Hildegard Ganter, Jacek Nadobny, Horst Fähling, Martin Seebass, Roland Felix, Peter Wust pages 267-277 Abstract | Full Text | Full-Text PDF (618 KB)
The effect of an endorectal balloon and off-line correction on the interfraction systematic and random prostate position variations: A comparative study Emile N.J. Th. van Lin, Lisette P. van der Vight, J. Alfred Witjes, HenkJan J. Huisman, Jan Willem Leer, Andries G. Visser pages 278-288 Abstract | Full Text | Full-Text PDF (821 KB)
Atlas-based automatic segmentation of MR images: Validation study on the brainstem in radiotherapy context Pierre-Yves Bondiau, Grégoire Malandain, Stéphane Chanalet, Pierre-Yves Marcy, Jean-Louis Habrand, François Fauchon, Philippe Paquis, Adel Courdi, Olivier Commowick, Isabelle Rutten, Nicholas Ayache pages 289-298 Abstract | Full Text | Full-Text PDF (547 KB)
Letters to the Editor
Accelerated hypofractionation Minesh Mehta, Jack Fowler pages 299-300 Full Text | Full-Text PDF (92 KB)
In response to Drs. Mehta and Fowler Patrick C.F. Cheung, Yee C. Ung, Cyril E. Danjoux pages 300-301 Full Text | Full-Text PDF (75 KB)
In response to Drs. Mehta and Fowler Raymond P. Abratt, Alistair J. Hunter pages 301-302 Full Text | Full-Text PDF (54 KB)
Predictors of radiation pneumonitis after radiotherapy in lung cancer Branislav Jeremic, Michael Hennig, Frank B. Zimmermann page 302 Full Text | Full-Text PDF (42 KB)
Establishing a prognostic score for primary CNS lymphomas Andrés J.M. Ferreri, Michele Reni pages 303-304 Full Text | Full-Text PDF (72 KB)
In response to Drs. Ferreri and Reni Eric Bessell, Sarah Lewis, Francesc Graus pages 304-305 Full Text | Full-Text PDF (58 KB)
Prostate brachytherapy as monotherapy: Are there gaps, holes, and islands in the argument in regard to Wallner et al. (Int J Radiat Oncol Biol Phys 2003;57:1297–1303) James Rubenstein page 305 Full Text | Full-Text PDF (44 KB)
In response to Dr. Rubenstein Kent Wallner, Gregory Merrick, Daniel Reed pages 305-306 Full Text | Full-Text PDF (56 KB)
ACARA As conformal as reasonably achievable Michel Schlienger page 306 Full Text | Full-Text PDF (42 KB)
Letters to the editor
Can post–RT FDG PET accurately predict the pathologic status in neck dissection after radiation for locally advanced head and neck cancer? In regard to Rogers et al. (Int J Radiat Oncol Biol Phys 2004;58:694–697) Min Yao, John M. Buatti, Kenneth J. Dornfeld, Michael M. Graham, Russell B. Smith, Gerry F. Funk, Henry T. Hoffman pages 306-307 Full Text | Full-Text PDF (56 KB)
In response to Dr. Yao et al. Kathryn McConnell Greven page 307 Full Text | Full-Text PDF (44 KB)
Planning trials with fibrosis-preventing agents Violetta F. Dubrovskaya, Alexei B. Chukhlovin pages 307-308 Full Text | Full-Text PDF (57 KB)
In response to Drs. Ubrovskaya and Chukhlovin Akihito Nishioka, Yasuhiro Ogawa, Hikaru Ueno pages 308-309 Full Text | Full-Text PDF (64 KB)
Modeling prostate cancer: In regards to Nahum et al. (Int J Radiat Oncol Biol Phys 2003;57:391–401) Jian Z. Wang, Nina A. Mayr, X. Allen Li, Robert D. Stewart pages 309-310 Full Text | Full-Text PDF (67 KB)
In response to Dr. Wang et al. Alan Nahum, J.D. Chapman pages 310-311 Full Text | Full-Text PDF (62 KB)
Prevention of pterygium recurrence by postoperative single-dose β-irradiation: A prospective randomized clinical double-blind trial Dexter Y.L. Leung, Felix C.H. Li, Dennis S.C. Lam pages 311-312 Full Text | Full-Text PDF (64 KB)
In response to Dr. Leung et al. Ina-M. Jürgenliemk-Schulz, Lidy J.C. Hartman, Judith M. Roesink, Robbert J.H.A. Tersteeg, Ingeborg van de Tweel, Henk B. Kal, Maarten P. Mourits, Harm K. Wijrdeman page 312 Full Text | Full-Text PDF (49 KB)
Dose–response relationship for radiation-induced cancer—decrease or plateau at high dose: In regard to Davis (Int J Radiat Oncol Biol Phys 2004;59:916) Uwe Schneider pages 312-313 Full Text | Full-Text PDF (57 KB)
In response to Dr. Schneider Robert H. Davis page 313 Full Text | Full-Text PDF (37 KB)
Meetings and news notes pages 314-315 Full-Text PDF (40 KB)
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