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Issue Highlights page A11 Full Text | Full-Text PDF (32 KB)
Report
American Society for Therapeutic Radiology and Oncology (ASTRO) Emerging Technology Committee Report on Electronic Brachytherapy Catherine C. Park, Sue S. Yom, Matthew B. Podgorsak, Eleanor Harris, Robert A. Price, Alison Bevan, Jean Pouliot, Andre A. Konski, Paul E. Wallner, Electronic Brachytherapy Working Group pages 963-972 Abstract | Full Text | Full-Text PDF (1117 KB) | Add-Ons
Rapid Communication
Imaging Primary Lung Cancers in Mice to Study Radiation Biology David G. Kirsch, Jan Grimm, Alexander R. Guimaraes, Gregory R. Wojtkiewicz, Bradford A. Perez, Philip M. Santiago, Nikolas K. Anthony, Thomas Forbes, Karen Doppke, Ralph Weissleder, Tyler Jacks pages 973-977 Abstract | Full Text | Full-Text PDF (882 KB) | Add-Ons
Clinical Investigations
Breast
Outcome After Conservative Surgery and Breast Irradiation in 5,717 Patients With Breast Cancer: Implications for Supraclavicular Nodal Irradiation, 19 June 2009 Lorenzo Livi, Vieri Scotti, Calogero Saieva, Icro Meattini, Beatrice Detti, Gabriele Simontacchi, Carla Deluca Cardillo, Fabiola Paiar, Monica Mangoni, Livia Marrazzo, Benedetta Agresti, Luigi Cataliotti, Simonetta Bianchi, Giampaolo Biti pages 978-983 Abstract | Full Text | Full-Text PDF (106 KB)
True Local Recurrence Rate in the Conserved Breast After Magnetic Resonance Imaging–Targeted Radiotherapy, 06 July 2009 Elisabeth Whipp, Mark Beresford, Elinor Sawyer, Michael Halliwell pages 984-990 Abstract | Full Text | Full-Text PDF (420 KB)
Four-Year Efficacy, Cosmesis, and Toxicity Using Three-Dimensional Conformal External Beam Radiation Therapy to Deliver Accelerated Partial Breast Irradiation, 09 June 2009 Peter Y. Chen, Michelle Wallace, Christina Mitchell, Inga Grills, Larry Kestin, Ashley Fowler, Alvaro Martinez, Frank Vicini pages 991-997 Abstract | Full Text | Full-Text PDF (117 KB)
Radiosensitization of Chemotherapy-Refractory, Locally Advanced or Locally Recurrent Breast Cancer With Trastuzumab: A Phase II Trial, 29 June 2009 Janet K. Horton, Jan Halle, Madlyn Ferraro, Lisa Carey, Dominic T. Moore, David Ollila, Carolyn I. Sartor pages 998-1004 Abstract | Full Text | Full-Text PDF (145 KB)
Rectum
Late Side Effects and Quality of Life After Radiotherapy for Rectal Cancer, 19 June 2009 Kjersti Bruheim, Marianne G. Guren, Eva Skovlund, Marianne J. Hjermstad, Olav Dahl, Gunilla Frykholm, Erik Carlsen, Kjell Magne Tveit pages 1005-1011 Abstract | Full Text | Full-Text PDF (151 KB)
Sexual Function in Males After Radiotherapy for Rectal Cancer, 02 November 2009 Kjersti Bruheim, Marianne G. Guren, Alv A. Dahl, Eva Skovlund, Lise Balteskard, Erik Carlsen, Sophie D. Fosså, Kjell Magne Tveit pages 1012-1017 Abstract | Full Text | Full-Text PDF (259 KB)
Tumor Volume Changes Assessed by Three-Dimensional Magnetic Resonance Volumetry in Rectal Cancer Patients After Preoperative Chemoradiation: The Impact of the Volume Reduction Ratio on the Prediction of Pathologic Complete Response, 03 August 2009 Jeong Hyun Kang, Young Chul Kim, Hyunki Kim, Young Wan Kim, Hyuk Hur, Jin Soo Kim, Byung Soh Min, Hogeun Kim, Joon Seok Lim, Jinsil Seong, Ki Chang Keum, Nam Kyu Kim pages 1018-1025 Abstract | Full Text | Full-Text PDF (459 KB)
Anal Canal
Clinical Utility of the Modified Segmental Boost Technique for Treatment of the Pelvis and Inguinal Nodes, 13 July 2009 M.S. Moran, W.A. Castrucci, M. Ahmad, H. Song, M.W. Lund, S. Mani, Daniel Chamberlain, S.A. Higgins pages 1026-1036 Abstract | Full Text | Full-Text PDF (3748 KB)
Liver
Feasibility and Efficacy of Single Photon Emission Computed Tomography-Based Three-Dimensional Conformal Radiotherapy for Hepatocellular Carcinoma 8 cm or More With Portal Vein Tumor Thrombus in Combination With Transcatheter Arterial Chemoembolization, 19 June 2009 Shintaro Shirai, Morio Sato, Kazuhiro Suwa, Kazushi Kishi, Chigusa Shimono, Tetsuo Sonomura, Nobuyuki Kawai, Hirohiko Tanihata, Hiroki Minamiguchi, Motoki Nakai pages 1037-1044 Abstract | Full Text | Full-Text PDF (912 KB)
Bladder
Cone Beam CT Imaging Analysis of Interfractional Variations in Bladder Volume and Position During Radiotherapy for Bladder Cancer, 19 June 2009 Don Yee, Matthew Parliament, Satyapal Rathee, Sunita Ghosh, Lawrence Ko, Brad Murray pages 1045-1053 Abstract | Full Text | Full-Text PDF (586 KB)
Prostate
Health-Related Quality of Life up to Six Years After 125I Brachytherapy for Early-Stage Prostate Cancer, 25 January 2010 Ellen M.A. Roeloffzen, Irene M. Lips, Marion P.R. van Gellekom, Joep van Roermund, Steven J. Frank, Jan J. Battermann, Marco van Vulpen pages 1054-1060 Abstract | Full Text | Full-Text PDF (246 KB)
Postoperative Nomogram Predicting the 9-Year Probability of Prostate Cancer Recurrence After Permanent Prostate Brachytherapy Using Radiation Dose as a Prognostic Variable, 19 June 2009 Louis Potters, Mack Roach, Brian J. Davis, Richard G. Stock, Jay P. Ciezki, Michael J. Zelefsky, Nelson N. Stone, Paul A. Fearn, Changhong Yu, Katsuto Shinohara, Michael W. Kattan pages 1061-1065 Abstract | Full Text | Full-Text PDF (205 KB)
A Small Tolerance for Catheter Displacement in High–Dose Rate Prostate Brachytherapy is Necessary and Feasible, 21 July 2009 Albert Tiong, Sean Bydder, Martin Ebert, Nikki Caswell, David Waterhouse, Nigel Spry, Peter Camille, David Joseph pages 1066-1072 Abstract | Full Text | Full-Text PDF (561 KB)
Intraoperative Radiotherapy During Radical Prostatectomy for Locally Advanced Prostate Cancer: Technical and Dosimetric Aspects, 21 July 2009 Marco Krengli, Carlo Terrone, Andrea Ballarè, Gianfranco Loi, Roberto Tarabuzzi, Giansilvio Marchioro, Debora Beldì, Eleonora Mones, Cesare Bolchini, Alessandro Volpe, Bruno Frea pages 1073-1077 Abstract | Full Text | Full-Text PDF (252 KB)
Whole-Pelvis Radiotherapy in Combination With Interstitial Brachytherapy: Does Coverage of the Pelvic Lymph Nodes Improve Treatment Outcome in High-Risk Prostate Cancer?, 24 June 2009 Nathan Bittner, Gregory S. Merrick, Kent E. Wallner, Wayne M. Butler, Robert Galbreath, Edward Adamovich pages 1078-1084 Abstract | Full Text | Full-Text PDF (315 KB)
Phase II Study of Vinorelbine and Estramustine in Combination With Conformational Radiotherapy for Patients With High-Risk Prostate Cancer, 06 July 2009 Joan Carles, Miguel Nogue, Josep M. Sole, Palmira Foro, Montserrat Domenech, Marta Suarez, Enrique Gallardo, Darío García, Ferrán Ferrer, Antoni Gelabert-Mas, Javier Gayo, Xavier Fabregat pages 1085-1091 Abstract | Full Text | Full-Text PDF (139 KB)
Daily Isocenter Correction With Electromagnetic-Based Localization Improves Target Coverage and Rectal Sparing During Prostate Radiotherapy, 21 July 2009 Ramji Ramaswamy Rajendran, John P. Plastaras, Rosemarie Mick, Diane McMichael Kohler, Alireza Kassaee, Neha Vapiwala pages 1092-1099 Abstract | Full Text | Full-Text PDF (820 KB)
Lung
Comparative Survival in Patients With Postresection Recurrent Versus Newly Diagnosed Non–Small-Cell Lung Cancer Treated With Radiotherapy, 19 June 2009 Xu-Wei Cai, Lu-Ying Xu, Li Wang, James A. Hayman, Andrew C. Chang, Allan Pickens, Kemp B. Cease, Mark B. Orringer, Feng-Ming Kong pages 1100-1105 Abstract | Full Text | Full-Text PDF (520 KB)
Variations in Target Volume Definition for Postoperative Radiotherapy in Stage III Non–Small-Cell Lung Cancer: Analysis of an International Contouring Study, 29 June 2009 Femke O.B. Spoelstra, Suresh Senan, Cecile Le Péchoux, Satoshi Ishikura, Francesc Casas, David Ball, Allan Price, Dirk De Ruysscher, John R. van Sörnsen de Koste, Lung Adjuvant Radiotherapy Trial Investigators Group pages 1106-1113 Abstract | Full Text | Full-Text PDF (571 KB)
Permanent Iodine-125 Interstitial Planar Seed Brachytherapy for Close or Positive Margins for Thoracic Malignancies, 19 June 2009 Subhakar Mutyala, Alexandra Stewart, Atif J. Khan, Robert A. Cormack, Desmond O'Farrell, David Sugarbaker, Phillip M. Devlin pages 1114-1120 Abstract | Full Text | Full-Text PDF (247 KB)
The Impact of Radiation Dose and Fractionation on Outcomes for Limited-Stage Small-Cell Lung Cancer, 07 August 2009 Natsuo Tomita, Takeshi Kodaira, Toyoaki Hida, Hiroyuki Tachibana, Tatsuya Nakamura, Rie Nakahara, Haruo Inokuchi pages 1121-1126 Abstract | Full Text | Full-Text PDF (114 KB)
Head and Neck
Quantitative Analysis of Extracapsular Extension of Metastatic Lymph Nodes and its Significance in Radiotherapy Planning in Head and Neck Squamous Cell Carcinoma, 03 August 2009 Pirus Ghadjar, Heide Schreiber-Facklam, Ruth Gräter, Christina Evers, Mathew Simcock, Andreas Geretschläger, Norbert M. Blumstein, Peter Zbären, Yitzhak Zimmer, Ludwig Wilkens, Daniel M. Aebersold pages 1127-1132 Abstract | Full Text | Full-Text PDF (387 KB)
Hypothyroidism After Radiotherapy for Nasopharyngeal Cancer Patients, 13 July 2009 Yuan-Hua Wu, Hung-Ming Wang, Hellen Hi-Wen Chen, Chien-Yu Lin, Eric Yen-Chao Chen, Kang-Hsing Fan, Shiang-Fu Huang, I-How Chen, Chun-Ta Liao, Ann-Joy Cheng, Joseph Tung-Chieh Chang pages 1133-1139 Abstract | Full Text | Full-Text PDF (251 KB)
High-Dose-Rate Intraoperative Radiation Therapy for Recurrent Head-and-Neck Cancer, 29 June 2009 David J. Perry, Kelvin Chan, Suzanne Wolden, Michael J. Zelefsky, Johnny Chiu, Gilad Cohen, Marco Zaider, Dennis Kraus, Jatin Shah, Nancy Lee pages 1140-1146 Abstract | Full Text | Full-Text PDF (1096 KB)
Sarcoma
Primary Tumor Necrosis Predicts Distant Control in Locally Advanced Soft-Tissue Sarcomas After Preoperative Concurrent Chemoradiotherapy, 06 July 2009 Dhara M. MacDermed, Luke L. Miller, Terrance D. Peabody, Michael A. Simon, Hue H. Luu, Rex C. Haydon, Anthony G. Montag, Samir D. Undevia, Philip P. Connell pages 1147-1153 Abstract | Full Text | Full-Text PDF (232 KB)
Intraoperative Electron Radiotherapy for the Management of Aggressive Fibromatosis, 03 August 2009 Falk Roeder, Carmen Timke, Susanne Oertel, Frank W. Hensley, Marc Bischof, Marc W. Muenter, Juergen Weitz, Markus W. Buchler, Burkhard Lehner, Juergen Debus, Robert Krempien pages 1154-1160 Abstract | Full Text | Full-Text PDF (163 KB)
Pediatric Tumor
Locoregional Tumor Progression After Radiation Therapy Influences Overall Survival in Pediatric Patients With Neuroblastoma, 12 August 2009 Atmaram S. Pai Panandiker, Lisa McGregor, Matthew J. Krasin, Shengjie Wu, Xiaoping Xiong, Thomas E. Merchant pages 1161-1165 Abstract | Full Text | Full-Text PDF (210 KB)
Lymphoma
Comparison of Favorable Early-Stage Hodgkin's Lymphoma Treatments: A Single-Institution Review, 20 August 2009 Rajiv Samant, Ibraheem Alomary, Eyad Alsaeed, Badr Al-jasir, Isabelle Bence-Bruckler, Peter Cross, Paul Genest, Lothar Huebsch pages 1166-1170 Abstract | Full Text | Full-Text PDF (242 KB)
Brain
Early Expansion of the Intracranial CSF Volume After Palliative Whole-Brain Radiotherapy: Results of a Longitudinal CT Segmentation Analysis, 29 June 2009 Paul Sanghera, Sandra L. Gardner, Daryl Scora, Phillip Davey pages 1171-1176 Abstract | Full Text | Full-Text PDF (498 KB)
A Comparison of Volumetric Modulated Arc Therapy and Conventional Intensity-Modulated Radiotherapy for Frontal and Temporal High-Grade Gliomas, 29 June 2009 Richard Shaffer, Alan M. Nichol, Emily Vollans, Ming Fong, Sandy Nakano, Vitali Moiseenko, Moira Schmuland, Roy Ma, Michael McKenzie, Karl Otto pages 1177-1184 Abstract | Full Text | Full-Text PDF (582 KB)
Palliation
Management of Spinal Metastases From Renal Cell Carcinoma Using Stereotactic Body Radiotherapy, 24 July 2009 Quynh-Nhu Nguyen, Almon S. Shiu, Laurence D. Rhines, He Wang, Pamela K. Allen, Xin Shelley Wang, Eric L. Chang pages 1185-1192 Abstract | Full Text | Full-Text PDF (1819 KB)
Normal Tissues
Analysis of Clinical and Dosimetric Factors Associated With Change in Renal Function in Patients With Gastrointestinal Malignancies After Chemoradiation to the Abdomen, 19 June 2009 Kilian Salerno May, Nikhil I. Khushalani, Rameela Chandrasekhar, Gregory E. Wilding, Renuka V. Iyer, Wen W. Ma, Leayn Flaherty, Richard C. Russo, Marwan Fakih, Boris W. Kuvshinoff, John F. Gibbs, Milind M. Javle, Gary Y. Yang pages 1193-1198 Abstract | Full Text | Full-Text PDF (199 KB)
Biology Contributions
Increased Chromosomal Radiosensitivity in Women Carrying BRCA1/BRCA2 Mutations Assessed With the G2 Assay Beroukas Ernestos, Pandis Nikolaos, Giannoukakos Koulis, Rizou Eleni, Beroukas Konstantinos, Giatromanolaki Alexandra, Koukourakis Michael pages 1199-1205 Abstract | Full Text | Full-Text PDF (249 KB)
Accumulation of DNA Double-Strand Breaks in Normal Tissues After Fractionated Irradiation Claudia E. Rübe, Andreas Fricke, Juliane Wendorf, Annika Stützel, Martin Kühne, Mei Fang Ong, Peter Lipp, Christian Rübe pages 1206-1213 Abstract | Full Text | Full-Text PDF (3577 KB)
Significance of Interleukin-6 Signaling in the Resistance of Pharyngeal Cancer to Irradiation and the Epidermal Growth Factor Receptor Inhibitor Chih-Cheng Chen, Wen-Cheng Chen, Chang-Hsien Lu, Wen-Hung Wang, Paul-Yang Lin, Kuan-Der Lee, Miao-Fen Chen pages 1214-1224 Abstract | Full Text | Full-Text PDF (3128 KB) | Add-Ons
Inactivation of Kupffer Cells by Gadolinium Chloride Protects Murine Liver From Radiation-Induced Apoptosis Shi-Suo Du, Min Qiang, Zhao-Chong Zeng, Ai-Wu Ke, Yuan Ji, Zheng-Yu Zhang, Hai-Ying Zeng, Zhongshan Liu pages 1225-1234 Abstract | Full Text | Full-Text PDF (1427 KB)
Physics Contributions
Comparison of 18F-Fluorothymidine and 18F-Fluorodeoxyglucose PET/CT in Delineating Gross Tumor Volume by Optimal Threshold in Patients With Squamous Cell Carcinoma of Thoracic Esophagus, 11 November 2009 Dali Han, Jinming Yu, Yonghua Yu, Guifang Zhang, Xiaojun Zhong, Jie Lu, Yong Yin, Zheng Fu, Dianbin Mu, Baijiang Zhang, Wei He, Zhijun Huo, Xijun Liu, Lei Kong, Shuqiang Zhao, Xiangyu Sun pages 1235-1241 Abstract | Full Text | Full-Text PDF (1841 KB)
Quantification of Artifact Reduction With Real-Time Cine Four-Dimensional Computed Tomography Acquisition Methods, 24 November 2009 Ulrich W. Langner, Paul J. Keall pages 1242-1250 Abstract | Full Text | Full-Text PDF (1183 KB)
Effects of Prostate-Rectum Separation on Rectal Dose From External Beam Radiotherapy, 24 November 2009 Robert C. Susil, Todd R. McNutt, Theodore L. DeWeese, Danny Song pages 1251-1258 Abstract | Full Text | Full-Text PDF (3204 KB)
A Comparison of Dose–Response Models for the Parotid Gland in a Large Group of Head-and-Neck Cancer Patients, 14 December 2009 Antonetta C. Houweling, Marielle E.P. Philippens, Tim Dijkema, Judith M. Roesink, Chris H.J. Terhaard, Cornelis Schilstra, Randall K. Ten Haken, Avraham Eisbruch, Cornelis P.J. Raaijmakers pages 1259-1265 Abstract | Full Text | Full-Text PDF (392 KB) | Add-Ons
Dynamic Jaws and Dynamic Couch in Helical Tomotherapy, 11 November 2009 Florian Sterzing, Matthias Uhl, Henrik Hauswald, Kai Schubert, Gabriele Sroka-Perez, Yu Chen, Weiguo Lu, Rock Mackie, Jürgen Debus, Klaus Herfarth, Gustavo Oliveira pages 1266-1273 Abstract | Full Text | Full-Text PDF (569 KB)
Letters to the Editor
Response to “Predictors of Prostate Cancer–Specific Mortality in Elderly Men With Intermediate-Risk Prostate Cancer Treated With Brachytherapy With or Without External Beam Radiation Therapy” (Int J Radiat Oncol Biol Phys 2009, in press) Michael Froehner, Rainer Koch, Rainer J. Litz, Manfred P. Wirth page 1274 Full Text | Full-Text PDF (62 KB)
In Reply to Dr. Froehner et al Akash Nanda, Ming-Hui Chen, Anthony V. D'Amico page 1275 Full Text | Full-Text PDF (53 KB)
Capecitabine Initially Concomitant to Radiotherapy Then Perioperatively Administered in Locally Advanced Rectal Cancer. In Regard to MG Zampino et al. (Int J Radiat Oncol Biol Phys 2009;75:421-427) Mutahir A. Tunio, Altaf H. Hashmi page 1275 Full Text | Full-Text PDF (50 KB)
In Reply to Drs. Mutahir and Hashmi Maria Giulia Zampino, Elena Magni, Maria Cristina Leonardi, Fabrizio Luca pages 1275-1276 Full Text | Full-Text PDF (68 KB)
Response to “Helical Tomotherapy for Simultaneous Multitarget Radiotherapy for Pulmonary Metastasis.” (Int J Radiat Oncol Biol Phys 2009;75:703–710) Hideya Yamazaki page 1276 Full Text | Full-Text PDF (54 KB)
In Reply to Dr. Yamazaki Chul-Seung Kay pages 1276-1277 Full Text | Full-Text PDF (75 KB)
Response to “Intraoperative Radiotherapy During Radical Prostatectomy for Locally Advanced Prostate Cancer: Technical and Dosimetric Aspects” (Int J Radiat Oncol Biol Phys 2009; in press) John Thoms, Robert Bristow, Padraig Warde, Stéphane Supiot page 1277 Full Text | Full-Text PDF (58 KB)
In Reply to Dr. Thoms et al. Marco Krengli, Pierfrancesco Franco, Carlo Terrone, Alessandro Volpe, Giansilvio Marchioro page 1277 Full Text | Full-Text PDF (57 KB)
Fractionated Stereotactic Radiotherapy as Reirradiation for Locally Recurrent Head and Neck Cancer: In Regard to Roh et al (Int J Radiat Oncol Biol Phys. 2009 Aug 1;74(5):1348-55 Gozde Yazici, Mustafa Cengiz, Fadil Akyol page 1278 Full Text | Full-Text PDF (56 KB)
In Reply to Dr. Yazici et al. Yeon-Sil Kim, Kwang-Won Roh page 1278 Full Text | Full-Text PDF (51 KB)
Other Content
Meetings page 1279 Full Text | Full-Text PDF (50 KB)
ASTRO News page 1280 Full Text | Full-Text PDF (63 KB)
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