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Issue Highlights page A17 Full Text | Full-Text PDF (30 KB)
Late-Breaking Abstracts
Short-term Endocrine Therapy Prior to and during Radiation Therapy Improves Overall Survival in Patients with T1b-T2b Adenocarcinoma of the Prostate and PSA ≤ 20: Initial Results of RTOG 94-08 D.G. McGowan, D. Hunt, C.U. Jones, M. Amin, M.H. Leibenhaut, S.M. Husian, M. Rotman, L. Souhami, H. Sandler, W.U. Shipley page 1 Full Text | Full-Text PDF (47 KB)
A Phase III Trial to Test Accelerated Versus Standard Fractionation in Combination with Concurrent Cisplatin for Head and Neck Carcinomas (RTOG 0129): Report of Efficacy and Toxicity K. Ang, T. Pajak, R. Wheeler, D. Rosenthal, F. Nguyen-Tan, C. Lu, H. Kim, R. Axelrod, C. Silverman, R. Weber pages 1-2 Full Text | Full-Text PDF (49 KB)
Clinical Investigations
Head and Neck
Mature Results of a Randomized Trial of Accelerated Hyperfractionated Versus Conventional Radiotherapy in Head-and-Neck Cancer Michele I. Saunders, Ana M. Rojas, Mahesh K.B. Parmar, Stanley Dische, CHART Trial Collaborators pages 3-8 Abstract | Full Text | Full-Text PDF (196 KB)
Radiochemotherapy With Cetuximab, Cisplatin, and Amifostine for Locally Advanced Head and Neck Cancer: A Feasibility Study, 09 September 2009 Michael I. Koukourakis, Pelagia G. Tsoutsou, Antonios Karpouzis, Maria Tsiarkatsi, Ilias Karapantzos, Vassilios Daniilidis, Constantinos Kouskoukis pages 9-15 Abstract | Full Text | Full-Text PDF (119 KB)
Xerostomia After Treatment for Oral and Oropharyngeal Cancer Using the University of Washington Saliva Domain and a Xerostomia-Related Quality-of-Life Scale, 12 August 2009 Simon N. Rogers, Ian A. Johnson, Derek Lowe pages 16-23 Abstract | Full Text | Full-Text PDF (125 KB)
Lung
18F-FDG PET-CT Simulation for Non–Small-Cell Lung Cancer: Effect in Patients Already Staged by PET-CT, 07 August 2009 Gerard G. Hanna, Jonathan McAleese, Kathryn J. Carson, David P. Stewart, Vivian P. Cosgrove, Ruth L. Eakin, Ashraf Zatari, Tom Lynch, Peter H. Jarritt, V.A. Linda Young, Joe M. O'Sullivan, Alan R. Hounsell pages 24-30 Abstract | Full Text | Full-Text PDF (353 KB)
Quality of Life After Stereotactic Radiotherapy for Stage I Non-Small-Cell Lung Cancer, 27 October 2009 Noëlle C. van der Voort van Zyp, Jean-Briac Prévost, Bronno van der Holt, Cora Braat, Robertus J. van Klaveren, Peter M. Pattynama, Peter C. Levendag, Joost J. Nuyttens pages 31-37 Abstract | Full Text | Full-Text PDF (600 KB)
Predictive Factors of Late Radiation Fibrosis: A Prospective Study in Non–Small Cell Lung Cancer, 19 February 2010 Renaud Mazeron, Bénédicte Etienne-Mastroianni, David Pérol, Dominique Arpin, Michel Vincent, Lionel Falchero, Isabelle Martel-Lafay, Christian Carrie, Line Claude pages 38-43 Abstract | Full Text | Full-Text PDF (111 KB)
Esophagus
Influence of Irradiated Lung Volumes on Perioperative Morbidity and Mortality in Patients After Neoadjuvant Radiochemotherapy for Esophageal Cancer, 12 August 2009 Doreen Dähn, Joachim Martell, Hilke Vorwerk, Clemens F. Hess, Heinz Becker, Klaus Jung, Reinhard Hilgers, Hendrik Andreas Wolff, Robert Michael Hermann, Hans Christiansen pages 44-52 Abstract | Full Text | Full-Text PDF (193 KB)
Stomach
Interfraction and Respiratory Organ Motion During Conformal Radiotherapy in Gastric Cancer, 07 August 2009 Barbara Wysocka, Zahra Kassam, Gina Lockwood, James Brierley, Laura A. Dawson, Carol Ann Buckley, David Jaffray, Bernard Cummings, John Kim, Rebecca Wong, Jolie Ringash pages 53-59 Abstract | Full Text | Full-Text PDF (240 KB)
Rectum
Hyperfractionated Accelerated Radiotherapy for Rectal Cancer in Patients With Prior Pelvic Irradiation, 20 August 2009 Prajnan Das, Marc E. Delclos, John M. Skibber, Miguel A. Rodriguez-Bigas, Barry W. Feig, George J. Chang, Cathy Eng, Manpreet Bedi, Sunil Krishnan, Christopher H. Crane pages 60-65 Abstract | Full Text | Full-Text PDF (109 KB)
Predicting Grade 3 Acute Diarrhea During Radiation Therapy for Rectal Cancer Using a Cutoff-Dose Logistic Regression Normal Tissue Complication Probability Model, 07 August 2009 John M. Robertson, Matthias Söhn, Di Yan pages 66-72 Abstract | Full Text | Full-Text PDF (303 KB)
Anus
Comparison of Positron Emission Tomography Scanning and Sentinel Node Biopsy in the Detection of Inguinal Node Metastases in Patients With Anal Cancer, 24 July 2009 Massimiliano Mistrangelo, Ettore Pelosi, Marilena Bellò, Isabella Castellano, Paola Cassoni, Umberto Ricardi, Fernando Munoz, Patrizia Racca, Viviana Contu, Giancarlo Beltramo, Mario Morino, Antonio Mussa pages 73-78 Abstract | Full Text | Full-Text PDF (100 KB)
Lymphoma
Involved Field Radiation After Autologous Stem Cell Transplant for Diffuse Large B-Cell Lymphoma in the Rituximab Era, 03 August 2009 Tithi Biswas, Sughosh Dhakal, Rui Chen, Ollivier Hyrien, Steven Bernstein, Jonathan W. Friedberg, Richard I. Fisher, Jane Liesveld, Gordon Phillips, Louis S. Constine pages 79-85 Abstract | Full Text | Full-Text PDF (287 KB)
Primary Radiation Therapy in Patients With Localized Orbital Marginal Zone B-Cell Lymphoma of Mucosa-Associated Lymphoid Tissue (MALT Lymphoma), 24 July 2009 Seok Hyun Son, Byung Ock Choi, Gi Won Kim, Suk Woo Yang, Young Seon Hong, Ihl Bohng Choi, Yeon Sil Kim pages 86-91 Abstract | Full Text | Full-Text PDF (809 KB)
Brain
A Phase I Dose-Escalation Study (ISIDE-BT-1) of Accelerated IMRT With Temozolomide in Patients With Glioblastoma, 17 August 2009 Alessio G. Morganti, Mario Balducci, Maurizio Salvati, Vincenzo Esposito, Pantaleo Romanelli, Marica Ferro, Franco Calista, Cinzia Digesù, Gabriella Macchia, Massimo Ianiri, Francesco Deodato, Savino Cilla, Angelo Piermattei, Vincenzo Valentini, Numa Cellini, Gian Paolo Cantore pages 92-97 Abstract | Full Text | Full-Text PDF (103 KB)
Phase I/II Trial of Hyperfractionated Concomitant Boost Proton Radiotherapy for Supratentorial Glioblastoma Multiforme, 20 August 2009 Masashi Mizumoto, Koji Tsuboi, Hiroshi Igaki, Tetsuya Yamamoto, Shingo Takano, Yoshiko Oshiro, Yasutaka Hayashi, Haruko Hashii, Ayae Kanemoto, Hidetsugu Nakayama, Shinji Sugahara, Hideyuki Sakurai, Akira Matsumura, Koichi Tokuuye pages 98-105 Abstract | Full Text | Full-Text PDF (168 KB)
Incidence, Risks, and Sequelae of Posterior Fossa Syndrome in Pediatric Medulloblastoma, 20 August 2009 Mariam P. Korah, Natia Esiashvili, Claire M. Mazewski, Roger J. Hudgins, Mourad Tighiouart, Anna J. Janss, Frederick P. Schwaibold, Ian R. Crocker, Walter J. Curran, Robert B. Marcus pages 106-112 Abstract | Full Text | Full-Text PDF (181 KB)
Prospective Evaluation of Radiotherapy With Concurrent and Adjuvant Temozolomide in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma, 03 August 2009 Rakesh Jalali, Nirmal Raut, Brijesh Arora, Tejpal Gupta, Debnarayan Dutta, Anusheel Munshi, Rajiv Sarin, Purna Kurkure pages 113-118 Abstract | Full Text | Full-Text PDF (136 KB)
Bladder
A 10-Year Retrospective Review of a Nonrandomized Cohort of 458 Patients Undergoing Radical Radiotherapy or Cystectomy in Yorkshire, UK, 07 August 2009 Nicholas P. Munro, Subramnian K. Sundaram, Philip M.T. Weston, Lesley Fairley, Simon C.W. Harrison, David Forman, Rohit Chahal pages 119-124 Abstract | Full Text | Full-Text PDF (124 KB)
Prostate
Dose-Escalated Radiotherapy for High-Risk Prostate Cancer: Outcomes in Modern Era With Short-Term Androgen Deprivation Therapy, 20 August 2009 Stanley L. Liauw, Walter M. Stadler, David Correa, Ralph R. Weichselbaum, Ashesh B. Jani pages 125-130 Abstract | Full Text | Full-Text PDF (111 KB)
Relating Dose Outside the Prostate With Freedom From Failure in the Dutch Trial 68 Gy vs. 78 Gy, 09 December 2009 Marnix G. Witte, Wilma D. Heemsbergen, Román Bohoslavsky, Floris J. Pos, Abrahim Al-Mamgani, Joos V. Lebesque, Marcel van Herk pages 131-138 Abstract | Full Text | Full-Text PDF (1008 KB)
Biologically Effective Dose (BED) Correlation With Biochemical Control After Low–Dose Rate Prostate Brachytherapy for Clinically Low-Risk Prostate Cancer, 15 October 2009 Edward F. Miles, John W. Nelson, Ali K. Alkaissi, Shiva Das, Robert W. Clough, Gloria Broadwater, Mitchell S. Anscher, Junzo P. Chino, James R. Oleson pages 139-146 Abstract | Full Text | Full-Text PDF (443 KB)
Predictors of Prostate Cancer–Specific Mortality in Elderly Men With Intermediate-Risk Prostate Cancer Treated With Brachytherapy With or Without External Beam Radiation Therapy, 09 September 2009 Akash Nanda, Ming-Hui Chen, Brian J. Moran, Michelle H. Braccioforte, Daniel Dosoretz, Sharon Salenius, Michael Katin, Rudi Ross, Anthony V. D'Amico pages 147-152 Abstract | Full Text | Full-Text PDF (223 KB)
Dose Escalation to the Dominant Intraprostatic Lesion Defined by Sextant Biopsy in a Permanent Prostate I-125 Implant: A Prospective Comparative Toxicity Analysis, 07 August 2009 Marc Gaudet, Éric Vigneault, Sylviane Aubin, Nicolas Varfalvy, François Harel, L. Beaulieu, André-Guy Martin pages 153-159 Abstract | Full Text | Full-Text PDF (377 KB)
Detection of Local, Regional, and Distant Recurrence in Patients With PSA Relapse After External-Beam Radiotherapy Using 11C-Choline Positron Emission Tomography, 23 September 2009 Anthonius J. Breeuwsma, Jan Pruim, Alphons C.M. van den Bergh, Anna M. Leliveld, Rien J.M. Nijman, Rudi A.J.O. Dierckx, Igle J. de Jong pages 160-164 Abstract | Full Text | Full-Text PDF (914 KB)
A Prospective Study of Intrafraction Prostate Motion in the Prone vs. Supine Position, 12 August 2009 Richard B. Wilder, Lucy Chittenden, Albert V. Mesa, Jane Bunyapanasarn, Jeff Agustin, Jessica Lizarde, John Ravera, Kenneth M. Tokita pages 165-170 Abstract | Full Text | Full-Text PDF (103 KB)
Cervix
Toxicity Associated With Bowel or Bladder Puncture During Gynecologic Interstitial Brachytherapy, 20 August 2009 Anand P. Shah, Jonathan B. Strauss, Benjamin T. Gielda, Thomas W. Zusag pages 171-179 Abstract | Full Text | Full-Text PDF (1185 KB)
Breast
Prognostic Significance of Number of Positive Nodes: A Long-Term Study of One to Two Nodes Versus Three Nodes in Breast Cancer Patients Patricia Tai, Edward Yu, Kurian Joseph pages 180-187 Abstract | Full Text | Full-Text PDF (153 KB)
The Association Between Biological Subtype and Isolated Regional Nodal Failure After Breast-Conserving Therapy, 19 February 2010 Jennifer Y. Wo, Alphonse G. Taghian, Paul L. Nguyen, Rita Abi Raad, Meera Sreedhara, Jennifer R. Bellon, Julia S. Wong, Michele A. Gadd, Barbara L. Smith, Jay R. Harris pages 188-196 Abstract | Full Text | Full-Text PDF (138 KB)
Comparative Analysis of the Post-Lumpectomy Target Volume Versus the Use of Pre-Lumpectomy Tumor Volume for Early-Stage Breast Cancer: Implications for the Future Elizabeth M. Nichols, Anil A. Dhople, Majid M. Mohiuddin, Todd W. Flannery, Cedric X. Yu, William F. Regine pages 197-202 Abstract | Full Text | Full-Text PDF (1149 KB)
Sarcoma
Improved Survival With Radiation Therapy in High-Grade Soft Tissue Sarcomas of the Extremities: A SEER Analysis, 12 August 2009 Matthew Koshy, Shayna E. Rich, Majid M. Mohiuddin pages 203-209 Abstract | Full Text | Full-Text PDF (261 KB)
Pediatrics
Portal Hypertension in Children With Wilms' Tumor: A Report From the National Wilms' Tumor Study Group, 20 August 2009 Anne B. Warwick, John A. Kalapurakal, San-San Ou, Daniel M. Green, Pat A. Norkool, Susan M. Peterson, Norman E. Breslow pages 210-216 Abstract | Full Text | Full-Text PDF (396 KB)
Benign Disease
Radiotherapy for Symptomatic Vertebral Hemangiomas: Results of a Multicenter Study and Literature Review, 21 August 2009 Reinhard Heyd, M. Heinrich Seegenschmiedt, Dirk Rades, Cornelia Winkler, Hans T. Eich, Frank Bruns, Georg Gosheger, Normann Willich, Oliver Micke, German Cooperative Group on Radiotherapy for Benign Diseases pages 217-225 Abstract | Full Text | Full-Text PDF (400 KB)
Biology Contributions
Radiation-Induced Survivin Nuclear Accumulation is Linked to DNA Damage Repair Gianni Capalbo, Klaus Dittmann, Christian Weiss, Sebastian Reichert, Eva Hausmann, Claus Rödel, Franz Rödel pages 226-234 Abstract | Full Text | Full-Text PDF (1743 KB) | Add-Ons
Clonally Expanding Thymocytes Having Lineage Capability in Gamma-Ray–Induced Mouse Atrophic Thymus Takashi Yamamoto, Shin-ichi Morita, Rieka Go, Miki Obata, Yoshinori Katsuragi, Yukari Fujita, Yoshitaka Maeda, Minesuke Yokoyama, Yutaka Aoyagi, Hitoshi Ichikawa, Yukio Mishima, Ryo Kominami pages 235-243 Abstract | Full Text | Full-Text PDF (951 KB) | Add-Ons
Bystander Effects Induced by Medium From Irradiated Cells: Similar Transcriptome Responses in Irradiated and Bystander K562 Cells Robert Herok, Maria Konopacka, Joanna Polanska, Andrzej Swierniak, Jacek Rogolinski, Roman Jaksik, Ronald Hancock, Joanna Rzeszowska-Wolny pages 244-252 Abstract | Full Text | Full-Text PDF (774 KB) | Add-Ons
Targeting Polo-Like Kinase 1 Enhances Radiation Efficacy for Head-and-Neck Squamous Cell Carcinoma Kate Gerster, Wei Shi, Benjamin Ng, Shijun Yue, Emma Ito, John Waldron, Ralph Gilbert, Fei-Fei Liu pages 253-260 Abstract | Full Text | Full-Text PDF (448 KB) | Add-Ons
Mitigation Effect of an FGF-2 Peptide on Acute Gastrointestinal Syndrome After High-Dose Ionizing Radiation Lurong Zhang, Weimin Sun, Jianjun Wang, Mei Zhang, Shanmin Yang, Yeping Tian, Sadasivan Vidyasagar, Louis A. Peña, Kunzhong Zhang, Yongbing Cao, Liangjie Yin, Wei Wang, Lei Zhang, Katherine L. Schaefer, Lawrence J. Saubermann, Steven G. Swarts, Bruce M. Fenton, Peter C. Keng, Paul Okunieff pages 261-268 Abstract | Full Text | Full-Text PDF (691 KB)
Physics Contributions
A Novel Dose Constraint to Reduce Xerostomia in Head-and-Neck Cancer Patients Treated With Intensity-Modulated Radiotherapy, 25 January 2010 Lidia Strigari, Marcello Benassi, Giorgio Arcangeli, Vicente Bruzzaniti, Giuseppe Giovinazzo, Laura Marucci pages 269-276 Abstract | Full Text | Full-Text PDF (449 KB)
Comparison of Planned Dose Distributions Calculated by Monte Carlo and Ray-Trace Algorithms for the Treatment of Lung Tumors With CyberKnife: A Preliminary Study in 33 Patients, 09 December 2009 Ellen E. Wilcox, George M. Daskalov, Holly Lincoln, Richard C. Shumway, Bruce M. Kaplan, Joseph M. Colasanto pages 277-284 Abstract | Full Text | Full-Text PDF (188 KB)
Lung Dose for Minimally Moving Thoracic Lesions Treated With Respiration Gating, 25 January 2010 Ivaylo B. Mihaylov, Mirek Fatyga, Eduardo G. Moros, Jose Penagaricano, Fritz A. Lerma pages 285-291 Abstract | Full Text | Full-Text PDF (159 KB)
Impact of Gastric Filling on Radiation Dose Delivered to Gastroesophageal Junction Tumors, 20 January 2010 Myriam Bouchard, Mary Frances McAleer, George Starkschall pages 292-300 Abstract | Full Text | Full-Text PDF (496 KB)
Accurate Automatic Delineation of Heterogeneous Functional Volumes in Positron Emission Tomography for Oncology Applications, 29 January 2010 Mathieu Hatt, Catherine Cheze le Rest, Patrice Descourt, André Dekker, Dirk De Ruysscher, Michel Oellers, Philippe Lambin, Olivier Pradier, Dimitris Visvikis pages 301-308 Abstract | Full Text | Full-Text PDF (580 KB) | Add-Ons
Behavior of Lipiodol Markers During Image Guided Radiotherapy of Bladder Cancer, 04 February 2010 Xiangfei Chai, Marcel van Herk, Jeroen B. van de Kamer, Peter Remeijer, Axel Bex, Anja Betgen, Theo M. De Reijke, Maarten C.C.M. Hulshof, Floris J. Pos, Arjan Bel pages 309-314 Abstract | Full Text | Full-Text PDF (308 KB) | Add-Ons
Letters to the Editor
Quality of Radiotherapy Reporting in Randomized Controlled Trials of Hodgkin's Lymphoma and Non-Hodgkin's Lymphoma: In Regard to Bekelman and Yahalom (Int J Radiat Oncol Biol Phys 2009;73:492-498) Thomas J. FitzGerald, Maryann Bishop-Jodoin, M. Giulia Cicchetti, Richard Hanusik, Sandy Kessel, Fran Laurie, Kathleen M. McCarten, Janaki Moni, Richard S. Pieters, Nancy Rosen, Kenneth Ulin, Marcia Urie, Allen R. Chauvenet, Louis S. Constine, James Deye, Bhadrasain Vikram, Debra Friedman, Robert B. Marcus, Nancy P. Mendenhall, Jon L. Williams, James Purdy, Joel Saltz, Cindy L. Schwartz, Keith S. White, Suzanne Wolden pages 315-316 Full Text | Full-Text PDF (83 KB)
Response to “Benefit of Radiation Boost After Whole-Breast Radiotherapy” (Int J Radiat Oncol Biol Phys 2009;75:1029–1034) Adri C. Voogd, Maurice J.C. van der Sangen page 316 Full Text | Full-Text PDF (52 KB)
In Reply to Drs. Voogd and van der Sangen Lorenzo Livi, Gabriele Simontacchi, Icro Meattini, Giampaolo Biti page 316 Full Text | Full-Text PDF (52 KB)
In Regard to Kased N et al. (Int J Radiat Oncol Biol Phys 2009;75:1132–1140) Eduardo Weltman, Reynaldo André Brandt page 316 Full Text | Full-Text PDF (52 KB)
In Response to Drs. Weltman and Brandt Norbert Kased, Penny K. Sneed page 317 Full Text | Full-Text PDF (48 KB)
Response to “Unacceptable Cosmesis in a Protocol Investigating Intensity-Modulated Radiotherapy With Active Breathing Control for Accelerated Partial-Breast Irradiation” (Int J Radiat Oncol Biol Phys 2010;76:71–78) and “Toxicity of Three-Dimensional Conformal Radiotherapy for Accelerated Partial Breast Irradiation” Int J Radiat Oncol Biol Phys 2009;75:1290–1296) Norman Wolmark, Walter J. Curran, Frank Vicini, Julia White, Joseph P. Costantino, Douglas Arthur, Robert Kuske, Rachel Rabinovitch, Thomas B. Julian, David S. Parda page 317 Full Text | Full-Text PDF (50 KB)
In Response to Dr. Wolmark and Colleagues Reshma Jagsi, Merav Ben-David, Jean Moran, Robin Marsh, Kent Griffith, James Hayman, Lori Pierce page 318 Full Text | Full-Text PDF (34 KB)
Other Content
Meetings page 319 Full Text | Full-Text PDF (49 KB)
ASTRO News page 320 Full Text | Full-Text PDF (58 KB)
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