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PET studies can provide information related to tumor metabolic activities. This information may facilitate targeted dose delivery to improve local tumor control. In this study, we perform feasibility tests on PET-image guided dose escalation in high-dose rate brachytherapy (HDR). Robustness of the planning is tested, and plan quality and potential outcome significance are evaluated.

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Author Disclosure: E.K. Lee, None; F. Yuan, None; A. Templeton, None; R. Yao, None; J.C. Chu, None.

 

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