Radium-223 Outcomes After Multiple Lines of Metastatic Castration–Resistant Prostate Cancer Therapy in Clinical Practice: Implication of Pretreatment Spinal Epidural Disease

      MRI is not routinely performed prior to initiating radium-223 to document spinal epidural disease. However, radium-223 decays to form alpha-particles with very short path lengths that may not reach the epidural space. Herein, we investigate the impact of baseline spinal epidural disease on metastatic castration-resistant prostate cancer (mCRPC) patients treated with radium-223.
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